Anti-EPHB1 Antibody detects endogenous levels of total EPHB1 protein.
EPHB1(ephrin type-B receptor 1) belongs to the Eph gene family of receptor tyrosine kinases. It is present in venous endothelial cells during embryonic development to adulthood. It is located on human chromosome 3q22.2.
Immunogen
The antiserum was produced against synthesized peptide derived from human EPHB1/2/3.
Immunogen Range: 631-680
Biochem/physiol Actions
EPHB1(ephrin type-B receptor 1) participates in carcinogenesis of RCC (renal cell carcinoma). It plays a major role in the growth of nervous and vascular system. It acts as a biomarker for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Schwann cells (SC) enter the central nervous system (CNS) in pathophysiological conditions. However, how SC invade the CNS to remyelinate central axons remains undetermined. We studied SC migratory behavior ex vivo and in vivo after exogenous transplantation in the demyelinated
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