SAB4500363

Anti-Collagen I α2 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): α 2 type i collagen, co1a2, col1a2, collagen, type i
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 129 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P08123
• UniProt accession no.: P08123
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... COL1A2(1278)

Description

General description

Anti-Collagen I α2 Antibody detects endogenous levels of total Collagen I α2 protein.

Collagen I α2 (COL1A2) is located on human chromosome 7q22.1. Human COL1A2 gene consists of two dinucleotide repeats: one in the 5′-flanking region of the gene, made of of poly(dC–dA) and poly(dC–dG) and the other in the first intron comprised of poly(dG–dT).

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen I alpha2.

Immunogen Range: 471-520

Application

Anti-Collagen I α2 antibody has been used to quantify protein expression levels after western blotting.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Biochem/physiol Actions

Collagen I α2 (COL1A2) is essential to maintain elasticity of the vessel wall and is an important constituent of the extracellular matrix. Mutations in COL1A2 results in osteogenesis imperfecta (OI).

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable