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Key Documents

SAB4301496

Sigma-Aldrich

Anti-phospho-NF-κB p65 (pSer281) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

NFKB3, Nuclear factor NF-kappa-B p65 subunit, RELA, TF65, p65

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

65 kDa

species reactivity

rat, human, mouse

concentration

1.0 mg/mL

technique(s)

western blot: 1:500-1:1000 (Cell Lysate)

isotype

IgG

accession no.

NP_001138610.1

UniProt accession no.

Q04206

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer281)

Gene Information

human ... RELA(5970)

Specificity

The antibody detects endogenous level of NF- kappaB p65 only when phosphorylated at serine 281.

Immunogen

Peptide sequence around phosphorylation site of serine281(E-L-S(p)-E-P) derived from Human NF- kappaB .

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
461212000

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Zhihong Liu et al.
Molecular medicine reports, 17(1), 612-617 (2017-11-09)
Pneumonia is a common respiratory disease worldwide, which is preventable and treatable; however, it is recognized as a leading cause of mortality in children. The present study aimed to investigate the role and mechanism of microRNA (miR)‑20a in inflammation in
T Fedchenko et al.
PPAR research, 2022, 7537210-7537210 (2022-06-07)
The master clock, which is located in the suprachiasmatic nucleus (SCN), harmonizes clock genes present in the liver to synchronize life rhythms and bioactivity with the surrounding environment. The reversed feeding disrupts the expression of clock genes in the liver.
Jianfeng Chen et al.
BMC cardiovascular disorders, 20(1), 240-240 (2020-05-22)
This study aimed to investigate the regulatory effect of rno-microRNA-30c-5p (rno-miR-30c-5p) on myocardial ischemia reperfusion (IR) injury in rats and the underlying molecular mechanisms. A rat model of myocardial IR injury was established. The infarct size was detected by 2,3,5-triphenyltetrazolium
Minghui Ou et al.
Molecular therapy. Nucleic acids, 21, 542-554 (2020-07-28)
Pulmonary arterial hypertension (PAH) is a fatal cardiovascular disease that could eventually result in right ventricular failure. Recently, the roles of microRNAs (miRNAs) in PAH have been highlighted. The present study aims to investigate the effects of miRNA (miR)-340-5p on

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