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SAB4301426

Sigma-Aldrich

Anti-phospho-SirT1 (pSer47) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

NAD-dependent deacetylase sirtuin 1, SIR1, SIR2L1, hSIR2, hSIRT1

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100 μL
$363.00

$363.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μL
$363.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$363.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

110 kDa

species reactivity

human

concentration

1.0 mg/mL

technique(s)

western blot: 1:500-1:1000 (Cell Lysate)

isotype

IgG

accession no.

NP_001135970.1

UniProt accession no.

Q96EB6

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer47)

Gene Information

human ... SIRT1(23411)

Specificity

The antibody detects endogenous level of SirT1 only when phosphorylated at serine 47.

Immunogen

Peptide sequence around phosphorylation site of serine 47(E-R-S(p)-P-G) derived from Human SirT1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
461211926

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Jessica D Panes et al.
Frontiers in pharmacology, 11, 709-709 (2020-06-12)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive impairment that increasingly afflicts the elderly population. Soluble oligomers (AβOs) has been implicated in AD pathogenesis: however, the molecular events underlying a role for Aβ are not well understood. We
Claudio Molinari et al.
Foods (Basel, Switzerland), 10(8) (2021-08-28)
Glaucoma is currently the leading cause of irreversible blindness; it is a neuropathy characterized by structural alterations of the optic nerve, leading to visual impairments. The aim of this work is to develop a new oral formulation able to counteract

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