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Key Documents

SAB4301326

Sigma-Aldrich

Anti-phospho-Connexin 43 (pTyr265) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

CX43, CXA1, CXN-43, GJA1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

43 kDa

species reactivity

human

concentration

1.0 mg/mL

technique(s)

western blot: 1:500-1:1000

accession no.

NP_000156.1.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr265)

Gene Information

human ... GJA1(2697)

Specificity

Connexin 43 antibody detects endogenous levels of Connexin 43 only when phosphorylated at Tyrosine 265

Immunogen

Peptide sequence around phosphorylation site of Tyrosine 265(Q-K-Y(p)-A-Y) derived from Human Connexin 43.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Lise Hangaard et al.
American journal of physiology. Cell physiology, 312(4), C385-C397 (2017-01-27)
Communication between vascular smooth muscle cells (VSMCs) is dependent on gap junctions and is regulated by the Na-K-ATPase. The Na-K-ATPase is therefore important for synchronized VSMC oscillatory activity, i.e., vasomotion. The signaling between the Na-K-ATPase and gap junctions is unknown.

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