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SAB4301240

Sigma-Aldrich

Anti-phospho-PKA α/β CAT (pThr197) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

PKACA, PRKACA, PRKACB

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100 μL
$484.00

$484.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μL
$484.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$484.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

40 kDa

species reactivity

mouse, human

concentration

1.0 mg/mL

technique(s)

immunohistochemistry: 1:100-1:200
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000 (Cell Lysate)

isotype

IgG

accession no.

NP_002721.1.

UniProt accession no.

P17612

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr197)

Gene Information

human ... PRKACA(5566)

Specificity

The antibody detects endogenous levels of PKA α/β CAT only when phosphorylated at threonine 197.

Immunogen

Peptide sequence around phosphorylation site of threonine 197(R-T-W(p)-T-L) derived from Human PKA α/β CAT.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
461211667

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Wanxu Guo et al.
Biology open, 10(5) (2020-10-14)
Podocytes are the major target in proteinuric kidney diseases such as diabetic nephropathy. The underlying molecular mechanisms by which high glucose (HG) results in podocyte damage remain unclear. This study investigated the regulatory role of Smad3, ezrin, and protein kinase
Jianrong Xu et al.
International journal of molecular medicine, 40(2), 499-504 (2017-06-29)
The model of urotensin II (UII)-induced cardiomyocyte hypertrophy has been widely used in studies on hypertrophy. However, the molecular mechanisms responsible for UII-induced cardiomyocyte hypertrophy have not yet been fully elucidated. It has been demonstrated that cardiomyocyte hypertrophy induced by UII

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