The antibody detects endogenous levels of total ABL1/2 protein.
Immunogen
Peptide sequence around aa. 391-395 (D-T-Y-T-A), according to the protein NP_005148.2, NP_001129472.1
Features and Benefits
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Target description
Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Certificates of Analysis (COA)
Lot/Batch Number
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