SAB4300631

Anti-phospho-Ephrin-B2 (pTyr³¹⁶) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-EPLG5, Anti-HTKL, Anti-Htk-L, Anti-LERK5
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~37 kDa
• species reactivity: mouse, rat, human
• concentration: 1 mg/mL
• technique(s): western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (P-V-Yp-I-V)
• NCBI accession no.: NM_004093.2
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr316)
• Gene Information: human ... SEPTIN1(1948)

Description

General description

The antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.

Immunogen

Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Yp-I-V), according to the protein NP_004084.1

Features and Benefits

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Target description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5′ UTR but that encode the same protein have been identified for this gene.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable