SAB4300358

Anti-KDR (Ab-951) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CD309 antibody produced in rabbit, Anti-FLK1 antibody produced in rabbit, Anti-VEGFR antibody produced in rabbit, Anti-VEGFR2 antibody produced in rabbit, Anti-kinase insert domain receptor (a type III receptor tyrosine kinase) antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~230 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (K-D-Y-V-G)
• NCBI accession no.: NP_002244.1
• UniProt accession no.: P35968
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KDR(3791)

Description

Immunogen

Peptide sequence around aa. 949-953 (K-D-Y-V-G), according to the protein KDR.

Features and Benefits

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Target description

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable