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SAB4300250

Sigma-Aldrich

Anti-phospho-SMAD1 (pSer465) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-BSP1 antibody produced in rabbit, Anti-JV4-1 antibody produced in rabbit, Anti-JV41 antibody produced in rabbit, Anti-MADH1 antibody produced in rabbit, Anti-SMAD family member 1 antibody produced in rabbit

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100 μG
$395.00

$395.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μG
$395.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$395.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~55 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(I-S-S-V-SP)

NCBI accession no.

NP_001003688.1

UniProt accession no.

Q15797

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer465)

Gene Information

human ... SMAD1(4086)

Immunogen

Peptide sequence around phosphorylation site of serine 465 (I-S-S-V-S(p)), according to the protein SMAD1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
951411321

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Chao-Ming Chen et al.
Cryobiology, 89, 82-89 (2019-05-09)
Recycled autografts have been commonly used in biological reconstruction in conjunction with wide bone resection. Extracorporeal irradiation (ECIR) and freezing are the two major options for pretreating tumor-bearing autografts before transplant. This study, for the first time, compared the effects
Raquel Escrich et al.
The Journal of nutritional biochemistry, 64, 218-227 (2018-12-21)
Breast cancer is the most common malignancy in women worldwide, and dietary lipids are important environmental factors influencing its etiology. We have investigated the effects, and the mechanisms associated, of high-fat diets on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors. Animals were fed
Jinghua Gui et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(10), 4352-4361 (2019-02-15)
At the level of organ formation, tissue morphogenesis drives developmental processes in animals, often involving the rearrangement of two-dimensional (2D) structures into more complex three-dimensional (3D) tissues. These processes can be directed by growth factor signaling pathways. However, little is
Xin-Yue Zhang et al.
Cellular signalling, 55, 109-118 (2019-01-12)
Bone morphogenetic protein 6 (BMP6) and transforming growth factor-β1 (TGF-β1) are key intraovarian regulators that play essential roles in regulating mammalian follicular function and promoting oocyte maturation. Furin, a member of the subtilisin-like proprotein convertase family, promotes the activation of
Shuo Wang et al.
Nature communications, 10(1), 2707-2707 (2019-06-22)
Bone metastases occur in most advanced breast cancer patients and cause serious skeletal-related complications. The mechanisms by which bone metastasis seeds develop in primary tumors and specifically colonize the bone remain to be elucidated. Here, we show that forkhead box
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