SAB4300217

Anti-phospho-CREB1 (pSer¹²⁹) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CREB antibody produced in rabbit, Anti-MGC9284 antibody produced in rabbit, Anti-cAMP responsive element binding protein 1 antibody produced in rabbit
• MDL number: MFCD01092316
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~43 kDa
• species reactivity: human, mouse, rat
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (I-L-SP-R-R)
• NCBI accession no.: NP_004370.1
• UniProt accession no.: P16220
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer129)
• Gene Information: human ... CREB1(1385)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 129 (I-L-S(p)-R-R), according to the protein CREB1.

Features and Benefits

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Target description

This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable