SAB4300097

Anti-phospho-CDC25C (pSer²¹⁶) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CDC25 antibody produced in rabbit, Anti-cell division cycle 25 homolog C (S. pombe) antibody produced in rabbit
• MDL number: MFCD00802890
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~60 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• isotype: IgG
• immunogen sequence: (S-P-SP-M-P)
• NCBI accession no.: NP_001781.2
• UniProt accession no.: P30307
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer216)
• Gene Information: human ... CDC25C(995)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 216 (S-P-S(p)-M-P), according to the protein CDC25C.

Features and Benefits

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Target description

cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclinB-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiplealternatively spliced transcript variants of this gene have been described, however, the full-length nature of many ofthem is not known.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable