SAB4300065

Anti-phospho-ICAM1 (pTyr⁵¹²) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-BB2 antibody produced in rabbit, Anti-CD54 antibody produced in rabbit, Anti-P3.58 antibody produced in rabbit, Anti-intercellular adhesion molecule 1 antibody produced in rabbit
• MDL number: MFCD00240668
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~92 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (K-K-YP-R-L)
• NCBI accession no.: NP_000192.2
• UniProt accession no.: P05362
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr512)
• Gene Information: human ... ICAM1(3383)

Description

Immunogen

Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y(p)-R-L)., according to the protein ICAM1.

Features and Benefits

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Target description

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable