flow cytometry: 5-10 μg/test using HeLa cells. immunoblotting: suitable immunofluorescence: 2-4 μg/mL using MCF7 cells. immunohistochemistry: 20 μg/mL using human liver tissue sections.
Monoclonal Anti-ZBBX (mouse IgG2a isotype) is derived from the hybridoma Zbx-7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide. Zinc finger Bbox domain-containing protein 1 (ZBBX) is located on chromosome 3q26.1. It is a member of the B-box family.
Specificity
Monoclonal Anti- ZBBX recognizes human ZBBX.
Immunogen
synthetic peptide corresponding to an internal sequence of human ZBBX
Application
Monoclonal Anti-ZBBX antibody produced in mouse may be used in:
immunoblotting
flow cytometry
immunofluorescence
immunohistochemistry
Biochem/physiol Actions
Zinc finger Bbox domain-containing protein 1 (ZBBX) number variations is associated with attention deficit hyperactivity disorder (ADHD), a common and persistent condition, which involves developmentally atypical and impairing inattention, impulsiveness and hyperactivity. It also functions as a tumor suppressor gene in hepatocellular carcinoma (HCC).
Physical form
Supplied as a solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as a preservative.
Storage and Stability
For extended storage, freeze at -20 °C in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Attention deficit hyperactivity disorder (ADHD) is a common and persistent condition characterized by developmentally atypical and impairing inattention, hyperactivity, and impulsiveness. We identified de novo and rare copy number variations (CNVs) in 248 unrelated ADHD patients using million-feature genotyping arrays.
Journal of hepatology, 52(6), 921-929 (2010-04-14)
Hepatocellular carcinoma (HCC) is a deadly cancer, whose incidence is increasing worldwide. Albeit the main risk factors for HCC development have been clearly identified, such as hepatitis B and C virus infection and alcohol abuse, there is still preliminary understanding
Methods (San Diego, Calif.), 73, 54-70 (2014-12-20)
Studies of the brain's transcriptome have become prominent in recent years, resulting in an accumulation of datasets with somewhat distinct attributes. These datasets, which are often analyzed only in isolation, also are often collected with divergent goals, which are reflected
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