SAB4200601

Monoclonal Anti-SLC5A7 antibody produced in mouse

~1.0 mg/mL, clone 62-2E8, purified immunoglobulin

• Synonym(s): Anti-MGC126299, Anti-MGC126300, Anti-SLC5A7, Anti-carrier family 5 (choline transporter), member 7, Anti-CHT, Anti-CHT1, Anti-Choline transporter, Anti-Hact, Anti-hCHT
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 62-2E8, monoclonal
• form: buffered aqueous solution
• mol wt: antigen ~72 kDa
• species reactivity: mouse, canine, human, bovine, monkey, chicken
• concentration: ~1.0 mg/mL
• technique(s): immunoblotting: 2-4 μg/mL using SK-Mel-28 total cell extracts; immunocytochemistry: suitable; immunofluorescence: 5-10 μg/mL using HEK-293T cells
• isotype: IgG1
• UniProt accession no.: Q92945
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KHSRP(8570)

Description

General description

Monoclonal Anti-SLC5A7 (mouse IgG1 isotype) is derived from the hybridoma 62-2E8 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human SLC5A7 recombinant fusion protein.

Specificity

Monoclonal Anti- SLC5A7 recognizes human, bovine, monkey, chicken, dog and mouse SLC5A7.

Immunogen

human SLC5A7 recombinant fusion protein

Application

Monoclonal Anti-SLC5A7 antibody produced in mouse may be used in:

• immunoblotting
• immunofluorescence
• immunocytochemistry

Biochem/physiol Actions

Solute carrier family 5 (sodium/choline cotransporter), member 7 (SLC5A7) is responsible for the reuptake of choline, the rate-limiting step in acetylcholine synthesis from the synaptic cleft into presynaptic neurons. A significant dysfunction of cholinergic neurotransmission is observed in a number of neurodegenerative disorders such as Alzheimer′s and Parkinson′s disease.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Storage and Stability

For extended storage, freeze at -20 °C in working aliquots. Repeated freezing and thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable