SAB4200440

Anti-COG5 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Synonym(s): Anti-13S Golgi transport complex 90 kDa subunit, Anti-COG complex subunit 5, Anti-Component of oligomeric Golgi complex 5, Anti-Conserved oligomeric Golgi complex subunit 5, Anti-GTC-90, Anti-Golgi transport complex 1
• UNSPSC Code: 12352203
• Human Protein Atlas Number: HPA020300
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~100 kDa
• species reactivity: human, rat, mouse
• concentration: ~1.0 mg/mL
• technique(s): western blot: 2-4 μg/mL using whole extracts of HEK-293T cells overexpressing human COG5.
• UniProt accession no.: Q9UP83
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... COG5(10466) ; mouse ... Cog5(238123) ; rat ... Cog5(298945)

Description

General description

Conserved oligomeric Golgi complex 5 (COG5), also known as CDG2I, GTC90 and GOLTC1, is a member of the conserved oligomeric Golgi (COG) complex. The complex is an evolutionarily conserved multisubunit protein COG complex. COG is composed of eight distinct subunits organized in two heterotrimeric groups, Cog2-Cog3-Cog4 and Cog5-Cog6-Cog7, which are linked by the dimeric group formed by Cog1 and Cog8.

Immunogen

peptide corresponding to the C-terminal region of human COG5, conjugated to KLH. The corresponding sequence is identical in mouse, rat, canine and monkey COG5.

Application

Anti-COG5 antibody produced in rabbit has been used in immunoblotting.

Biochem/physiol Actions

Conserved Oligomeric Golgi complex 5 (COG5) complex that regulates membrane trafficking and maintenance of Golgi glycosylation machinery in eukaryotic cells. Mutations in COG5 gene result in congenital disorder of glycosylation type 2I.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable