SAB4200368

Anti-LRIG3 antibody, Mouse monoclonal

clone LRG3-3, purified from hybridoma cell culture

• Synonym(s): Monoclonal Anti-LRIG3 antibody produced in mouse, Anti-FLJ90440, Anti-KIAA3016, Anti-leucine-rich repeats and immunoglobulin-like domains 3
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified from hybridoma cell culture
• antibody product type: primary antibodies
• clone: LRG3-3, monoclonal
• form: buffered aqueous solution
• mol wt: antigen ~125 kDa
• species reactivity: human
• concentration: ~1.0 mg/mL
• technique(s): flow cytometry: suitable; indirect immunofluorescence: suitable; western blot: 1.0-2.0 μg/mL using extracts of H1395 cells
• isotype: IgG1
• UniProt accession no.: Q6UXM1
• shipped in: dry ice
• Storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LRIG3(121227)

Description

General description

Monoclonal Anti-LRIG3 (mouse IgG1 isotype) is derived from the hybridoma LRG3-3 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a peptide corresponding to a sequence at the N-terminus human LRIG3 conjugated to KLH. Leucine-rich and immunoglobulin-like domain 3 (LRIG3) belongs to the family of LRIG. LRIG3 mRNA is widely expressed, with the highest levels in the stomach, skin and thyroid.

Immunogen

a peptide corresponding to a sequence at the N-terminus human LRIG3, conjugated to KLH. The corresponding sequence is identical in monkey and share high homology with rat and mouse LRIG3.

Application

Monoclonal Anti-LRIG3 antibody produced in mouse has been used in:

• immunoblotting
• immunofluorescence
• flow cytometry (FACS)

Biochem/physiol Actions

Leucine-rich and immunoglobulin-like domain 3 (LRIG3) is implicated in tumorigenesis, psoriasis, neural crest development and complex tissue morphogenesis. LRIG3 interacts with the ErbB family of receptors and Netrin 1.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable