SAB4200233

Anti-VIP36/ LMAN2 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Synonym(s): Anti-GP36B, glycoprotein GP36b, Anti-Lectin, mannose-binding 2, Anti-Vesicular integral protein of 36 kDa
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~36 kDa
• species reactivity: mouse, human, rat
• concentration: ~1.0 mg/mL
• technique(s): western blot: 2.5-5.0 μg/mL using whole extracts of human HeLa or ACHN cells, rat Rat2 or mouse 3T3 cells.
• UniProt accession no.: Q12907
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LMAN2(10960) ; mouse ... Lman2(66890) ; rat ... Lman2(290994)

Description

General description

Anti-VIP36/LMAN2 is produced in rabbit using as immunogen a synthetic peptide of human LMAN2 conjugated to KLH. VIP36 (vesicular-integral protein of 36 kDa) is a member of the leguminous-type (L-type) lectin family, which also includes ERGIC-53, ERGL and VIPL. L-type lectins are type I transmembrane proteins composed of a large luminal domain comprising a carbohydrate recognition domain (CRD) and a short cytosolic domain that mediates sorting within the early secretory pathway. VIP36 localizes mainly to the Golgi apparatus and cycles between the Golgi and the ER.

Application

Anti-VIP36/ LMAN2 antibody produced in rabbit has been used in immunoblotting.

Biochem/physiol Actions

Vesicular-integral protein of 36 kDa (VIP36) binds high mannose type glycoproteins in a Ca²⁺-dependent manner and may facilitate their sorting, trafficking and quality control.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable