SAB4200168

Anti-Importin 4 (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Synonym(s): Anti-IPO4, Anti-Ran-binding protein 4, Anti-imp4b, Anti-ranBP4
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~120 kDa
• species reactivity: human
• concentration: ~1.0 mg/mL
• technique(s): immunoprecipitation (IP): 2.5-5.0 μg using HepG2 cell lysates; indirect immunofluorescence: 1.25-2.5 μg/mL using HEK-293T cells overexpressing human Importin 4; western blot: 1-2 μg/mL using HepG2 cell lysates
• UniProt accession no.: Q8TEX9
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IPO4(79711)

Description

General description

Importin 4 is a member of importin protein family. It is a 119 kDa protein.

Immunogen

synthetic peptide corresponding to a sequence at the N-terminal of human Importin 4

Application

Anti-Importin 4 (N-terminal) antibody produced in rabbit has been used in several immunochemical techniques including immunoblotting, immunoprecipitation and immunofluorescence.

Biochem/physiol Actions

Importins can mediate the nuclear import of a diverse set of protein or RNA cargoes. Importins were implicated in anti-aggregation activity of highly basic cargo like histones and ribosomal proteins and in preventing their undesired interactions with other cellular components. It has been identified as an import factor for ribosomal protein rpS3a, the vitamin D receptor (VDR) and the sperm transition protein transition protein 2 (TP2).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable