SAB4100327

Monoclonal Anti-ADIPOQ antibody produced in mouse

clone ADIPOQ-A277, culture supernatant

• Synonym(s): Anti-ACDC, Anti-ACRP30, Anti-ADIPQTL1, Anti-ADPN, Anti-APM-1, Anti-APM1, Anti-Adiponectin, C1Q and collagen domain containing, Anti-GBP28
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: ADIPOQ-A277, monoclonal
• form: aqueous solution
• mol wt: antigen predicted mol wt 24.9 kDa
• species reactivity: human
• technique(s): western blot: suitable
• isotype: IgG1
• UniProt accession no.: Q15848
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... ADIPOQ(9370)

Description

General description

Adiponectin (ADIPOQ) gene is mapped to human chromosome 3q27.3. The gene codes for a 244 amino acid protein with four distinct regions. ADIPOQ is secreted by the adipocytes and is a most abundant circulating hormone.

Immunogen

ADIPOQ purified recombinant protein

Biochem/physiol Actions

Adiponectin (ADIPOQ) is an adipocyte specific secreted protein that circulates in the plasma. The protein has a C-terminal globular domain and an NH2-terminal collagen domain. It has anti-atherosclerotic and anti-inflammatory properties. ADIPOQ has a role in physiological processes such as energy homeostasis and obesity. It exhibits anti-diabetic action by interacting with adiponectin receptors, AdipoR1 and AdipoR2. Low levels of adiponectin are also linked with hypertension and dyslipidemia. Mutation in the gene encoding it is linked with risk for endometrial cancer.

Physical form

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable