SAB4100168

Monoclonal Anti-PRKAR2A antibody produced in mouse

clone PRKAR2A-A181, culture supernatant

• Synonym(s): Anti-PKR2, Anti-PRKAR2, Anti-Protein kinase A, RII-alpha subunit, Anti-Protein kinase, cAMP-dependent, regulatory, type II, alpha, Anti-Protein kinase, camp-dependent, regulatory, type II, α (PRKAR2A), Anti-cAMP-dependent protein kinase, regulatory subunit alpha 2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: PRKAR2A-A181, monoclonal
• form: aqueous solution
• mol wt: antigen predicted mol wt 45.3 kDa
• species reactivity: human
• technique(s): western blot: suitable
• UniProt accession no.: P13861
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... PRKAR2A(5576)

Description

General description

cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) is a regulatory subunit of a heterotetrametric protein, protein kinase A (PKA).. It exists as RIIα isoform of type II PKA. It is located on the human chromosome 3p21.3−p21.2.

Immunogen

PRKAR2A purified recombinant protein

Biochem/physiol Actions

cAMP-dependent protein kinase type II-α regulatory subunit (PRKAR2A) mediates the sub-cellular association by interacting to specific A-kinase anchoring proteins. It plays a key role in cyclic adenosine monophosphate (cAMP) signaling in eukaryotic cells, regulation of metabolism and cell growth. It is implicated in the protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

Physical form

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable