SAB4100162

Monoclonal Anti-GSTA4 antibody produced in mouse

clone GSTA4-A145, culture supernatant

• Synonym(s): Anti-GSTA4-4, Anti-GTA4, Anti-Glutathione S-transferase α 4
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: GSTA4-A145, monoclonal
• form: aqueous solution
• mol wt: antigen predicted mol wt 25.5 kDa
• species reactivity: human
• technique(s): western blot: suitable
• isotype: IgG1
• UniProt accession no.: O15217
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... GSTA4(2941)

Description

General description

GSTA4 (glutathione S-transferase α 4) gene is mapped to human chromosome 6p12.2. GSTA4 belongs to the superfamily of detoxification enzymes and is expressed widely.[1][2]

Immunogen

GSTA4 purified recombinant protein

Biochem/physiol Actions

GSTA4 (glutathione S-transferase α 4) catalyzes the conjugation of glutathione with 4-hydroxynonenal. The enzyme is known to deactivate 4-hydroxynonenal, a byproduct of lipid peroxidation which offers resistance against wound infection. GSTA4 is considered as a tumor susceptible gene that promotes the progression of skin cancer. Upregulation of GSTA4 was observed in erythroleukemia, mammary adenocarcinoma and ovary adenocarcinoma. GSTA4 might be associated with the development of drug resistance.[2][3][4]

Physical form

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable