ZIP6 is encoded by SLC39A6 (solute carrier family 39 member 6) gene. The gene has ten exons and 20864 bases. It is a multi-pass membrane protein and has a molecular weight of 85 kDa. ZIP6 is expressed at high levels in normal breast tissue, prostate, placenta, kidney, pituitary and corpus callosum. This gene is located on human chromosome 18q12.2.
Immunogen
ZIP6 antibody was raised against a 16 amino acid peptide near the center of human ZIP6.
Biochem/physiol Actions
ZIP6 (ZIP metal ion transporter family) controls the expression level of E-cadherin. It serves as a zinc influx transporter. SLC39A6 participates in the cellular invasion of HeLa cells by modulating the snail and slug expression mediated by ERK (extracellular signal–regulated kinase).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Linkage
The action of this antibody can be blocked using blocking peptide SBP3500597.
Physical form
Supplied in PBS with 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
SLC39A6 (solute carrier family 39 (zinc transporter), member 6)
Hamada S, et al.
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2011)
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
