Submandibular gland protein C (Smgc), also known as muc19 (mucin 19), belongs to the large gel-forming mucin family. It is secreted by the submandibular and sublingual glands in rodents. Smgc gene is mapped to mouse chromosome 15E3. The gene contains 60 exons and spans ~105kb on genomic DNA.
Immunogen
Peptide with sequence C-KLEPKYENPTNGS, from the internal region of the protein sequence according to NP_945121.1
Biochem/physiol Actions
Submandibular gland protein C (Smgc) might play an important role in the cyto-differentiation of mucous and seromucous acinar cells. It also acts as a marker for tubule secretory cells.
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Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
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Characterizing the complex composition of solid tumors is fundamental for understanding tumor initiation, progression and metastasis. While patient-derived samples provide valuable insight, they are heterogeneous on multiple molecular levels, and often originate from advanced tumor stages. Here, we use single-cell
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