Solute-linked carrier 26 member 6 anion transporter (SLC26A6) belongs to the solute carrier 26 gene family. It codes for an integral membrane protein, that has 10 or 12 transmembrane helices and intracellular amino and carboxy termininal. SLC26A6 is highly expressed in kidney and pancreas. This gene is located on human chromosome 3p21.
Immunogen
Peptide with sequence C-RDVAEYSEAKEVR, from the internal region of the protein sequence according to NP_075062.2; NP_599025.2; NP_602298.2; NP_001035544.1
Biochem/physiol Actions
Solute-linked carrier 26 member 6 anion transporter (SLC26A6), a multifunctional anion transporter plays a major role in the transport of oxalate anions. Aberrations in the SLC26A6 gene is linked with the threat of kidney stones.
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Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains
Lohi H, et al.
American Journal of Physiology. Cell Physiology, 284(3), C769-C779 (2003)
Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family
Waldegger S, et al.
Genomics, 72(1), 43-50 (2001)
Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger
Lohi H, et al.
Genomics, 70(1), 102-112 (2000)
In silico screening and molecular dynamic study of nonsynonymous single nucleotide polymorphisms associated with kidney stones in the SLC26A6 gene
Xiuli L, et al.
The Journal of Urology, 196(1), 118-123 (2016)
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