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SAB2501718

Sigma-Aldrich

Anti-COPS3 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

COP9 complex subunit 3, COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis), CSN3, SGN3

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100 μG
$586.00

$586.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μG
$586.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$586.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, canine, mouse, rat, bovine

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q9UNS2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... COPS3(8533)

General description

COPS3 (COP9 signalosome subunit 3) encodes the third subunit of an eight-subunit complex, the COP9 signalosome (CSN), and is located on chromosome 17p11.2.

Immunogen

Peptide with sequence C-SLYKKNIQRLT, from the internal region of the protein sequence according toNP_003644.2

Application

Anti-COPS3 antibody produced in goat is suitable for indirect ELISA and western blot applications.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0391P1
10391P1

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Yong-sheng Yu et al.
Cancer chemotherapy and pharmacology, 69(5), 1173-1180 (2012-01-13)
Csn3 (or CSN3) encodes the third subunit of an eight-subunit complex, the COP9 signalosome (CSN), which acts as a protein kinase and a deneddylase in mammalian cells. Previous studies have shown that Csn3 is essential for maintenance of cell proliferation
Joeri Both et al.
PloS one, 7(1), e30907-e30907 (2012-02-01)
Osteosarcoma is the most common primary malignancy of bone. The tumours are characterized by high genomic instability, including the occurrence of multiple regions of amplifications and deletions. Chromosome region 17p11.2-p12 is amplified in about 25% of cases. In previous studies

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