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SAB2501105

Sigma-Aldrich

Anti-VPS29, C-Terminal antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-DC15, Anti-DC7, Anti-DKFZp564F0223, Anti-FLJ20492, Anti-PEP11

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

canine, rat, human, mouse

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q9UBQ0

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... VPS29(51699)

Related Categories

Immunogen

Peptide with sequence C-DDVKVERIEYKKP from the C Terminus of the protein sequence according to NP_057310.1; NP_476528.1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yasir H Qureshi et al.
Cell reports, 38(3), 110262-110262 (2022-01-20)
Disruption of retromer-dependent endosomal trafficking is considered pathogenic in late-onset Alzheimer's disease (AD). Here, to investigate this disruption in the intact brain, we turn to a genetic mouse model where the retromer core protein VPS35 is depleted in hippocampal neurons
Eduardo J Pérez-Torres et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(26), e2118755119-e2118755119 (2022-06-25)
Retromer is a heteropentameric complex that plays a specialized role in endosomal protein sorting and trafficking. Here, we report a reduction in the retromer proteins-vacuolar protein sorting 35 (VPS35), VPS26A, and VPS29-in patients with amyotrophic lateral sclerosis (ALS) and in
Sabrina Simoes et al.
Cell reports, 37(13), 110182-110182 (2021-12-30)
Whether and how the pathogenic disruptions in endosomal trafficking observed in Alzheimer's disease (AD) are linked to its anatomical vulnerability remain unknown. Here, we began addressing these questions by showing that neurons are enriched with a second retromer core, organized

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