SAB2500130

Anti-ATF4 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-Activating transcription factor 4, Anti-CREB2, Anti-TAXREB67, Anti-TXREB
• MDL number: MFCD01092263
• UNSPSC Code: 12352203

Properties

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: P18848
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ATF4(468)

Description

General description

Activating transcription factor 4 (ATF4) is a transcription factor and the gene encoding it is localized on human chromosome 22q13.1.

Immunogen

Peptide with sequence C-EEVRKARGKKRVP from the C Terminus of the protein sequence according to NP_001666.

Biochem/physiol Actions

Activating transcription factor 4 (ATF4) acts as a master modulator of cellular adaptation to stress responses. It regulates the transcription of genes related to amino acid synthesis and import, redox balance and angiogenesis. The protein also has a role in the regulation of lipid metabolism. ATF4 is part of the unfolded protein response (UPR) pathway, which is activated in Alzheimer′s disease.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable