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Key Documents

SAB2108690

Sigma-Aldrich

Anti-MNX1

affinity isolated antibody

Synonym(s):

Anti- HLXB9, Anti- HOXHB9, Anti- SCRA1, Anti-HB9

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100 μL
$541.00

$541.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μL
$541.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$541.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

40 kDa

species reactivity

human

concentration

0.5-1 mg/mL

technique(s)

immunoblotting: suitable

accession no.

NM_005515

UniProt accession no.

P50219

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MNX1(3110)

General description

Motor neuron and pancreas homeobox 1 (MNX1) gene is located on human chromosome 7q36.3. MNX1 contains a homeodomain, which encodes transcriptional factors for both solid and hematological malignancies.

Immunogen

Synthetic peptide directed towards the N terminal region of human MNX1

Application

Anti-MNX1 produced in rabbit has been used in immunohistochemistry and western blotting.

Biochem/physiol Actions

Motor neuron and pancreas homeobox 1 (MNX1) is known to cause permanent neonatal diabetes mellitus (PNDM), which is a rare monogenic disease. In bladder cancer, MNX1 is upregulated.

Sequence

Synthetic peptide located within the following region: AAASGTGGGGGGGGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLA

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC1449

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Transcription factor gene MNX1 is a novel cause of permanent neonatal diabetes in a consanguineous family
Bonnefond, et al.
Diabetes and Metabolism, 39(3), 276-280 (2013)
Currarino syndrome and HPE microform associated with a 2.7-Mb deletion in 7q36. 3 excluding SHH gene
Coutton,, et al.
Molecular Syndromology, 5(1), 25-31 (2014)
The dual role of HLXB9 in leukemia
Ferguson,, et al.
Pediatric Blood & Cancer, 56(3), 349-352 (2011)
Motor neuron and pancreas homeobox 1/HLXB9 promotes sustained proliferation in bladder cancer by upregulating CCNE1/2
Chen, Min, et al.
Journal of Experimental & Clinical Cancer Research, 37(1), 154-154 (2018)

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