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SAB2105265

Sigma-Aldrich

Anti-IFI204 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Ifi16, Anti-p204

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

69 kDa

species reactivity

mouse, human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NM_008329

UniProt accession no.

P15092

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IFI16(3428)
mouse ... Ifi204(15951)

Related Categories

Immunogen

Synthetic peptide directed towards the middle region of mouse Ifi204

Biochem/physiol Actions

Ifi204 inhibits the transcription of ribosomal RNA.Ifi204 may inhibit DNA binding by UBTF. Ifi204 inhibits cell growth via TP53/p53 and RB1-dependent and independent pathways.Ifi204 acts as a coactivator of RUNX2 during osteogenesis. Ifi204 may be involved in macrophage differentiation.Ifi204 enables skeletal muscle and cardiac myocyte differentiation by sequestring Id proteins in the cytosol and promoting their ubiquitination and subsequent degradation.

Sequence

Synthetic peptide located within the following region: EAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQARTSTAQAGT

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mark N Lee et al.
Nature immunology, 14(2), 179-185 (2012-12-25)
The innate immune system senses viral DNA that enters mammalian cells, or in aberrant situations self-DNA, and triggers type I interferon production. Here we present an integrative approach that combines quantitative proteomics, genomics and small molecule perturbations to identify genes
Maolei Gong et al.
Biology of reproduction, 101(4), 733-747 (2019-07-28)
The seminal vesicles can be infected by microorganisms, thereby resulting in vesiculitis and impairment in male fertility. Innate immune responses in seminal vesicles cells to microbial infections, which facilitate vesiculitis, have yet to be investigated. The present study aims to
Lili Yu et al.
Immunology and cell biology, 93(2), 147-157 (2014-10-08)
Viruses can infect adipose tissues. However, innate antiviral responses in adipose cells and their effects on adipocyte function have not yet been intensively investigated. In this study, p204-initiated innate antiviral responses in mouse adipose cells were examined. Cytosolic DNA sensor

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