SAB2105261

Anti-HHEX, (C-terminal) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-Hex, Anti-Hhex-rs2, Anti-Prh, Anti-Prhx
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 30 kDa
• species reactivity: mouse, human
• concentration: 0.5 mg - 1 mg/mL
• technique(s): western blot: suitable
• NCBI accession no.: NM_008245
• UniProt accession no.: P43120
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... HHEX(3087) ; mouse ... Hhex(15242)

Description

Immunogen

Synthetic peptide directed towards the c terminal region of mouse Hhex

Biochem/physiol Actions

Hhex recognizes the DNA sequence 5′-ATTAA-3′. Hhex is a transcriptional repressor.It may play a role in hematopoietic differentiation.Hhex establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.

Sequence

Synthetic peptide located within the following region: SLDTSCEQGQDLPSEQNKGASLDRSQCSPSPASQEDPDSEISEDSDQEVD

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable