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Key Documents

SAB2103138

Sigma-Aldrich

Anti-RNH1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-MGC18200, Anti-MGC4569, Anti-MGC54054, Anti-RAI, Anti-RNH

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100 μL
$541.00

$541.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μL
$541.00

About This Item

MDL number:
MFCD08705587
UNSPSC Code:
12352203
NACRES:
NA.41

$541.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

50 kDa

species reactivity

rat, human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NM_203387

UniProt accession no.

P13489

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RNH1(6050)

General description

Ribonuclease/angiogenin inhibitor 1 (RNH1) is a cytoplasmic protein ubiquitously produced in all organs except testis. Rnh1 was first isolated from human placenta. The gene RNH1 is located in the human chromosome on 11p15.5.

Immunogen

Synthetic peptide directed towards the middle region of human RNH1

Biochem/physiol Actions

Ribonuclease/angiogenin inhibitor 1 (RNH1) has several leucine rich repeats which aids them in protein-protein interaction. Rnh1 binds with greater affinity and reversibly to members of ribonuclease 1 (RNase 1). Rnh1 has high affinity to angiogenin and inhibits its angiogenic functionality.

Sequence

Synthetic peptide located within the following region: LLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEG

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC25982

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An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract
Spencer JD, et al.
Kidney International, 85(5), 1179-1191 (2014)
A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci.
Richard 3rd CW, et al.
American Journal of Human Genetics, 52(5), 915-921 (1993)
Isolation and expression analysis of the human RNH2 gene encoding ribonuclease inhibitor 2
Miyamoto T and Hasuike S
Journal of Assisted Reproduction and Genetics, 19(8), 394-397 (2002)
Three decades of research on angiogenin: a review and perspective
Sheng J and Xu Z
Acta biochimica et biophysica Sinica, 48(5), 399-410 (2015)

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