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Key Documents

SAB2101601

Sigma-Aldrich

Anti-NKX2-5 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CSX, Anti-CSX1, Anti-NK2 transcription factor related, locus 5 (Drosophila), Anti-NKX2.5, Anti-NKX2E

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About This Item

UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

mol wt

35 kDa

species reactivity

bovine, horse, rat, canine, mouse, guinea pig, rabbit, human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

UniProt accession no.

P52952

storage temp.

−20°C

Gene Information

human ... NKX2-5(1482)

Immunogen

The immunogen for anti-NKX2-5 antibody: synthetic peptide derected towards the N terminal of human NKX2-5

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Sequence

Synthetic peptide located within the following region: ELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVE

Physical form

Lyophilized from PBS buffer with 2% sucrose

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC7930

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Ricardo Cortez Cardoso Penha et al.
BMC cancer, 18(1), 498-498 (2018-05-03)
NKX2.5 is a transcription factor transiently expressed during thyroid organogenesis. Recently, several works have pointed out the oncogenic role of NKX2.5 in a variety of tumors. We therefore hypothesized that NKX2.5 could also play a role in thyroid cancer. The
Kelly Elizabeth Sullivan et al.
Stem cell research & therapy, 5(1), 14-14 (2014-01-28)
Although stem cell therapy is a promising treatment for myocardial infarction, the minimal functional improvements observed clinically limit its widespread application. A need exists to maximize the therapeutic potential of these stem cells by first understanding what factors within the
Joshua R Gershlak et al.
Biochemical and biophysical research communications, 439(2), 161-166 (2013-09-03)
In this study we present a novel method for studying cellular traction force generation and mechanotransduction in the context of cardiac development. Rat hearts from three distinct stage of development (fetal, neonatal and adult) were isolated, decellularized and characterized via

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