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Key Documents

SAB1408179

Sigma-Aldrich

Anti-LOC91461 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

FLJ18197, MGC125960

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50 μG
$541.00

$541.00

Ships within 2 weeks. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)
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50 μG
$541.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$541.00

Ships within 2 weeks. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~33.3 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

NM_138370.1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SGK493(91461)

Related Categories

General description

Protein kinase domain containing, cytoplasmic homolog (PKDCC) is a secreted protein expressed in platelets. The gene encoding it is localized on human chromosome 2p21. Mouse polyclonal antibody raised against a full-length human LOC91461 protein.

Immunogen

LOC91461 (NP_612379.1, 1 a.a. ~ 294 a.a) full-length human protein.

Sequence
MVLLERLRHPNVLQLYGYCYQDSEDIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVDGELKVTDLDDARVEETPCAGSTDCILEFPARNFTLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLEKVLHLYRSGQYLQNSTASSSTEYQCIPDSTIPQEDYRCWPSYHHGSCLLSVFNLAEAVDVCESHAQCRAFVVTNQTTWTGRQLVFFKTGWSQVVPDPNKTTYVKASG

Biochem/physiol Actions

Protein kinase domain containing, cytoplasmic homolog (PKDCC) is crucial for embryonic development. It phosphorylates proteins associated with the endoplasmic reticulum and other secreted proteins. PKDCC has been linked to atopy.

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
08267

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A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS).
Castro-Giner F
BMC Medical Genetics, 10, 128-128 (2009)
A secreted tyrosine kinase acts in the extracellular environment.
Bordoli MR
Cell, 158(5), 1033-1044 (2014)

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