SAB1401543
Anti-C1QL1 antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
Synonym(s):
C1QRF, CRF
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... C1QL1(10882)
General description
C1QL1 (complement component 1 Q subcomponent-like 1) gene is conserved among the vertebrates. C1QL1 codes for a multimeric protein with 258 amino acid polypeptide and a hydrophobic signal sequence. The encoded protein consists of a collagenous region and a globular domain. The gene is broadly expressed in brain, predominantly in the brainstem.
Immunogen
C1QL1 (NP_006679.1, 1 a.a. ~ 258 a.a) full-length human protein.
Sequence
MLLVLVVLIPVLVSSGGPEGHYEMLGTCRMVCDPYPARGPGAGARTDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEPGKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD
Sequence
MLLVLVVLIPVLVSSGGPEGHYEMLGTCRMVCDPYPARGPGAGARTDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEPGKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD
Biochem/physiol Actions
RNA editing of C1QL1 is found to cause non-synonymous amino acid substitutions. The proteins belonging to the C1q/TNF (complement component 1 Q subcomponent-like 1/ tumor necrosis factor) family are known to be associated with numerous systems such as immune, endocrine, skeletal, neuronal, reproductive, sensory, and vascular systems. CTRPs are involved in the regulation of glucose metabolism.
Physical form
Solution in phosphate buffered saline, pH 7.4
Not finding the right product?
Try our Product Selector Tool.
Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
He Wang et al.
Biochemical and biophysical research communications, 522(1), 81-87 (2019-11-20)
Previous studies have shown that some inflammatory cytokines promote the expression of corticotropin-releasing hormone (CRH) in trophoblasts during pregnancy and that placental CRH could induce the production of adrenocorticotropic hormone (ACTH) in humans. However, whether the same is true in
Conserved recoding RNA editing of vertebrate C1q-related factor C1QL1.
Sie C P and Maas S
Febs Letters, 583(7), 1171-1174 (2009)
Cloning and characterization of CRF, a novel C1q-related factor, expressed in areas of the brain involved in motor function.
Berube N G, et al.
Brain Research Molecular Brain Research, 63(2), 233-240 (1999)
Anna Sałkowska et al.
Cells, 9(7) (2020-07-09)
Th17 cells are important players in host defense against pathogens such as Staphylococcus aureus, Candida albicans, and Bacillus anthracis. Th17 cell-mediated inflammation, under certain conditions in which balance in the immune system is disrupted, is the underlying pathogenic mechanism of
CTRP8 and CTRP9B are novel proteins that hetero-oligomerize with C1q/TNF family members.
Peterson JM, et al.
Biochemical and Biophysical Research Communications, 388(2), 360-365 (2009)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service