SAB1306277

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein, Osteocalcin
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 10963 Da
• species reactivity: human
• technique(s): immunohistochemistry: 1:50-1:100; western blot: 1:1000
• NCBI accession no.: NP_954642.1
• UniProt accession no.: P02818
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... BGLAP(632)

Description

General description

Bone γ-carboxyglutamate protein (BGLAP) or osteocalcin (OCN) is a non-collagenous bone matrix protein expressed by osteoblasts. It possesses a Gla (γ-carboxyglutamate) domain. The gene encoding OCN is localized on human chromosome 1q22.

Application

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit has been used in western blotting and immnuohistochemistry.

Biochem/physiol Actions

Bone γ-carboxyglutamate protein (BGLAP) regulates osteogenic differentiation of mesenchymal stromal cells. It has a role in bone turnover and mineralization. The protein also has a role in energy metabolism. BGLAP may act as a mediator between glucose metabolism and bone tissue.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable