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SAB1305536

Sigma-Aldrich

MONOCLONAL ANTI-HA TAG antibody produced in mouse

clone 12CA5, IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Tag from influenza hemagglutinin protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

mouse

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

12CA5, monoclonal

form

buffered aqueous solution

technique(s)

western blot: 1:1000

isotype

IgG2b

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

General description

Influenza virus hemagglutinin (HA) precursor is encoded by the gene mapped on segment 4. The encoded protein exists as trimers on the envelope of the virus and is a 76kDa surface glycoprotein.

Application

MONOCLONAL ANTI-HA TAG antibody produced in mouse has been used in Western blotting.

Biochem/physiol Actions

Influenza virus hemagglutinin (HA) acts as a key immunogen in avian influenza virus (AIV) vaccines. Activated HA facilitates virus attachment to oligosaccharide receptors on host cell surface and is involved in penetration through fusion following conformational modifications in the endolysosomal compartment. 226 and 228 residues in HA of the H3 subtype play a key role in host range restriction and receptor specificity.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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The role of influenza A virus hemagglutinin residues 226 and 228 in receptor specificity and host range restriction.
Vines A, et al.
Journal of Virology, 72(9) (1998)

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