Influenza virus hemagglutinin (HA) precursor is encoded by the gene mapped on segment 4. The encoded protein exists as trimers on the envelope of the virus and is a 76kDa surface glycoprotein.
Application
MONOCLONAL ANTI-HA TAG antibody produced in mouse has been used in Western blotting.
Biochem/physiol Actions
Influenza virus hemagglutinin (HA) acts as a key immunogen in avian influenza virus (AIV) vaccines. Activated HA facilitates virus attachment to oligosaccharide receptors on host cell surface and is involved in penetration through fusion following conformational modifications in the endolysosomal compartment. 226 and 228 residues in HA of the H3 subtype play a key role in host range restriction and receptor specificity.
Physical form
Supplied in PBS with 0.09% (W/V) sodium azide
Disclaimer
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Life science alliance, 1(5), e201800039-e201800039 (2018-11-21)
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