This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen
MUC20 (Q86ST8, 66-100) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MUC20.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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