PI4K2A, together with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) contributes to the overall PI4-kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).
Immunogen
PI4K2A (NP_060895, 1-30) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from N-terminal region of human PI4KII-M1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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