EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.
Immunogen
EDA (NP_001390, 52-86) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EDA.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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