SAB1300726

Anti-Phospho-SLAMF1-pY281 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-CD150 antigen, Anti-CDw150, Anti-IPO-3, Anti-SLAMF1, Anti-Signaling lymphocytic activation molecule [Precursor]
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): dot blot: suitable; indirect ELISA: 1:1000
• NCBI accession no.: NP_003028
• UniProt accession no.: Q13291
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr281)
• Gene Information: human ... SLAMF1(6504)

Description

General description

SLAMF1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

Immunogen

SLAMF1 (NP_003028, 264-296)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y281 of human SLAMF1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable