SAB1300696

Anti-OIT3(L) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-LZP, Anti-Liver-specific zona pellucida domain-containing protein, Anti-OIT3, Anti-Oncoprotein-induced transcript 3 protein [Precursor]
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI accession no.: NP_689848
• UniProt accession no.: Q8WWZ8
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... OIT3(170392)

Description

General description

Liver-specific ZP domain-containing protein (OIT3) is a liver-specific protein involved possibly in hepatocellular function and development. Oncoprotein induced transcript 3 (OIT3) is also known as liver-specific zona pellucida domain-containing protein and is composed of 545 amino acid residues. It is expressed in the liver and secreted into the blood. OIT3 possesses a D8C (domain with conserved eight cysteines) domain, an amino-terminal signal peptide and three epidermal growth factor (EGF)-like domains. The cDNA of the protein consists of 2,255bp. The gene encoding OIT3 is localized on human chromosome 10q21.3, spans 40kb and has nine exons.

Immunogen

OIT3 (NP_689848, )
This antibody is generated from rabbits immunized with a GST tag human OIT3 recombinant protein.

Biochem/physiol Actions

Oncoprotein induced transcript 3 (OIT3) may have a role in liver development and function. It has been shown to be downregulated in hepatocellular carcinoma.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable