SAB1300657

Anti-TPST1 (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): Anti-TPST-1, Anti-Tyrosylprotein sulfotransferase-1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: 1:1000
• NCBI accession no.: NP_003587
• UniProt accession no.: O60507
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TPST1(8460)

Description

General description

The importance of tyrosine O-sulfation in protein-protein interactions is illustrated by the sulfation of tyrosine residues in the leukocyte adhesion molecule P-selectin glycoprotein ligand-1; sulfation is required for its binding to P-selectin on activated endothelium. This enzyme represents a new class of Golgi sulfotransferases that catalyze tyrosine O-sulfation of many protein substrates involved in diverse physiologic functions including inflammation, hemostasis, body weight and reproductive physiology.

Immunogen

TPST1 (NP_003587, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TPST1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable