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Key Documents

SAB1300652

Sigma-Aldrich

Anti-ART1 (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1, Anti-Mono(ADP-ribosyl)transferase

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100 μG
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100 μG
$455.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$455.00


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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human

technique(s)

indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ART1(417)

General description

The amino acid sequence of ADP-ribosyltransferase 1 (ART1) consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. The gene encoding this protein is localized on human chromosome 11p15.4.

Immunogen

ART1 (NAR1_HUMAN, 19-53)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ART1.

Biochem/physiol Actions

ADP-ribosyltransferase 1 (ART1) catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of Escherichia coli. This protein has been associated with colon carcinoma.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Regulation of the RhoA/ROCK/AKT/?-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma.
Song GL
International Journal of Oncology (2016)
Expanded comparative mapping between man
and rabbit and detection of a new conserved
segment between HSA22 and OCU4
Chantry D
Cytogenetic and genome research (2011)
ADP-ribosylation of arginine
Sabrina Laing
Amino Acids (2011)

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