SAB1300628

Anti-DCAMKL3 (center) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): Anti-DCAMKL3, Anti-Doublecortin-like and CAM kinase-like 3, Anti-KIAA1765, Anti-Serine/threonine-protein kinase DCAMKL3
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: 1:1000
• NCBI accession no.: NP_208382
• UniProt accession no.: Q9C098
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... DCAMKL3(85443)

Description

General description

A predominant CaMK subfamily, the CaMKI/CaMKIV family, is thought to play a significant role in the central nervous system. The CaMKIV-related kinases, doublecortin and CaM kinase-Like (DCAMKL)1, DCAMKL2, and DCAMKL3, contain kinase domains with an intermediate homology not only to CaMKI/CaMKIV but also to CaMKII. The DCAMKL proteins are highly expressed in the central nervous system of mice, in a neuron-specific fashion. DCAMKL1 lacks the doublecortin-like domain (Dx). In contrast, DCAMKL2 contains a full N-terminal Dx, while possesses only a partial and dysfunctional Dx. Despite a large similarity in the kinase domain, the DCAMKL proteins have an impact on CRE-dependent gene expression distinct from that of the related CaMKI/CaMKIV and CaMKII subfamilies.

Immunogen

DCAMKL3 (XP_047355, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human DCAMKL3.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable