Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
Immunogen
KIS (Q8TAS1, 15-52) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terinal region of human KIS.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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