Retinoic acid plays a critical role in development, cellular growth, and differentiation and induces the expression of a variety of genes. RAI14 is expressed in retinal pigment epithelial cells, induced by all-trans-retinoic acid. Highest expression of RAI14 occurs in the placenta and testis. The predicted human RAI14 protein consists of 980 amino acids, and features 6 potential N-glycosylation sites, six ankyrin repeats and several coiled-coil helical domains. RAI14, which localizes to the cytoplasm, is also highly expressed in several human cancer cell lines. The precise cellular function of RAI14 remains to be determined.
Immunogen
RAI14 (NP_056392, 770-804) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human RAI14.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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