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Key Documents

S8432

Sigma-Aldrich

Sulfo NONOate disodium salt

Synonym(s):

Hydroxydiazenesulfonic acid 1-oxide disodium salt

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About This Item

Linear Formula:
N2O5SNa2
Molecular Weight:
186.06
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

form

powder

shipped in

dry ice

Storage temp.

−70°C

SMILES string

[Na+].[Na+].[O-]\N=[N+](/[O-])S([O-])(=O)=O

InChI

1S/H2N2O5S.2Na/c3-1-2(4)8(5,6)7;;/h3H,(H,5,6,7);;/q;2*+1/p-2/b2-1+;;

Inchi Key

LYIIGAIVRHASTQ-SEPHDYHBSA-L

Application

Does not release NO; useful as a negative control in NONOate research

Biochem/physiol Actions

SKI 5C was used to inhibit Sphingosine kinase 1 in SK-Hep1, HEK-293T cells.1

Pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Aneta Balcerczyk et al.
Free radical biology & medicine, 39(3), 327-335 (2005-07-05)
The specificity of 4-amino-5-methylamino-2',7'-difluorofluorescein (DAF-FM) for nitric oxide was evaluated in in vitro systems. The probe was found fairly specific for nitric oxide. Potential sources of artifacts include the autoxidation of DAF-FM, potentiated by light, and its oxidation by sources
C M Maragos et al.
Journal of medicinal chemistry, 34(11), 3242-3247 (1991-11-01)
Selected nucleophile/nitric oxide adducts [compounds which contain the anionic moiety, XN(O-)N = O] were studied for their ability to release nitric oxide spontaneously in aqueous solution and for possible vasoactivity. The diversity of structures chosen included those in which the

Articles

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

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