S6561
Anti-Sodium Channel, Brain Type II (α Subunit) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-BII, Anti-SP11II
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About This Item
MDL number:
UNSPSC Code:
12352203
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
rat, mouse
technique(s)
immunohistochemistry (frozen sections): 1:75 using using frozen brain tissue
immunoprecipitation (IP): suitable
western blot (chemiluminescent): 1:150-1:300
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Scn2a1(110876)
rat ... Scn2a1(24766)
Immunogen
synthetic peptide corresponding to amino acids 467-485 of the α subunit of rat type II voltage-gated sodium channel (VGSC, SP11II) with additional N-terminal lysine and tyrosine, conjugated to KLH. The epitope corresponds to the sequence in the intracellular loop between the I and II domains of type II VGSC α subunit.
Physical form
Lyophilized at ~0.3 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose, and 0.025% sodium azide.
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M Noda et al.
Nature, 322(6082), 826-828 (1986-08-03)
The voltage-gated sodium channel is a transmembrane protein essential for the generation of action potentials in excitable cells. It has been reported that sodium channels purified from the electric organ of the electric eel, Electrophorus electricus, and from chick cardiac
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