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S3071

Sigma-Aldrich

γ-Synuclein human

recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder

Synonym(s):

BCSG1

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Quality Level

assay

≥90% (SDS-PAGE)

form

lyophilized powder

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... SNCG(6623)

Biochem/physiol Actions

13.3 kDa (127 amino acids) protein, which plays a role in neurofilament network integrity. Member of a family of small, highly conserved synuclein proteins expressed primarily in neurons and in certain tumors.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Zhong-Zong Pan et al.
The Journal of biological chemistry, 277(38), 35050-35060 (2002-07-18)
Synucleins are a family of highly conserved small proteins predominantly expressed in neurons. Recently we and others have found that gamma-synuclein is dramatically up-regulated in the vast majority of late-stage breast and ovarian cancers and that gamma-synuclein over-expression can enhance
γ-Synuclein: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction.
Surguchov, A, et al.
Cell Motility, 49, 218-222 (2001)
Wei Wang et al.
BMC biochemistry, 12, 63-63 (2011-12-14)
D-serine is an important coagonist at the NR1 subunit of the NMDA receptor class of glutamate receptors. It is chiefly synthesized in the CNS by serine racemase (SR). Regulation of SR activity is still poorly understood. As step toward developing

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